一、基本信息

田慧彬，女，博士，副教授，硕士研究生导师

研究方向：羊基因编辑与脂质代谢调控

Email：tianhb@lzu.edu.cn

通讯地址：甘肃省兰州市城关区嘉峪关西路768号，邮编：730020

二、教育与工作经历

2023.03-至今，兰州大学，草地农业科技学院，副教授

2019.06-2023.02，西北农林科技大学，兽医学，博士后

2014.09-2019.06，西北农林科技大学，动物遗传育种与繁殖，博士

2010.09-2014.06，西北农林科技大学，生物科学创新实验班，学士

三、科研项目

1. 兰州大学人才引进科研启动费，2023-2028，主持

2. 国家自然科学基金青年项目，奶山羊C/EBPα基因调控乳腺脂肪酸代谢的分子机制研究，2021-2023，主持

3. 中国博士后科学基金面上项目，奶山羊FADS2基因对乳腺脂肪酸代谢的调控机理研究，2020-2022，主持

四、发表论文

1. Tian Huibin, Luo Jun*, Guo Peng, Li Chun, Zhang Xueying. C/EBPα promotes triacylglycerol synthesis via regulating PPARG promoter activity in goat mammary epithelial cells. Journal of Animal Science. 2023, 101, skac412.

2. Tian Huibin, Niu Huimin, Luo Jun*, Yao Weiwei, Chen Xiaoying, Wu Jiao, Geng Yanan, Gao Wenchang, Lei Anmin, Gao Zhimin, Tian Xiue, Zhao Xiaoe, Shi Huaiping, Li Cong, Hua Jinlian*. Knockout of stearoyl-CoA desaturase 1 decreased milk fat and unsaturated fatty acid contents of the goat model generated by CRISPR/Cas9. Journal of Agricultural and Food Chemistry. 2022, 70(13), 4030–4043.

3. Tian Huibin, Niu Huimin, Luo Jun*, Yao Weiwei, Gao Wenchang, Wen Yang, Cheng Min, Lei Anmin, Hua Jinlian*. Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis. PeerJ. 2022, 10:e13945.

4. Tian Huibin, Luo Jun*, Shi Hengbo, Chen Xiaoying, Wu Jiao, Liang Yusheng, Li Cong, Loor Juan J. Role of peroxisome proliferator-activated receptor-α on the synthesis of monounsaturated fatty acids in goat mammary epithelial cells. Journal of Animal Science. 2020, 98(3), skaa062.

5. Huang Lian#, Tian Huibin#, Luo Jun*, Song Ning, Wu Jiao. CRISPR/Cas9 based knockout of miR-145 affects intracellular fatty acid metabolism by targeting INSIG1 in goat mammary epithelial cells. Journal of Agricultural and Food Chemistry. 2020, 68(18), 5138-5146.

6. Tian Huibin, Luo Jun*, Zhang Zhifei, Wu Jiao, Zhang Tianying, Busato Sebastiano, Huang Lian, Song Ning, Bionaz Massimo*. CRISPR/Cas9-mediated stearoyl-CoA desaturase 1 (SCD1) deficiency affects fatty acid metabolism in goat mammary epithelial cells. Journal of Agricultural and Food Chemistry. 2018, 66(38), 10041-10052.