Dahurelmusin A, a hybrid Peptide–Polyketide from Elymus dahuricus infected by the Epichlo? bromicola endophyte

【来源:草地农业科技学院 | 发布日期:2017-08-11 | 作者:办公室 】    

Title: Dahurelmusin A, a hybrid Peptide–Polyketide from Elymus dahuricus infected by the Epichlo?  bromicola endophyte

Author: Song Qiuyan, Yu Haitao, Zhang Xingxu, Nan Zhibiao *, and Gao Kun *

Journal: Organic Letters

Impact Factor:IF2016=6.78(化学一区)

AbstractOne novel hybrid peptide-polyketide, dahurelmusin A (1), was isolated from Elymus dahuricus infected by the Epichloe? bromicola endophyte. Comprehensive spectroscopic analysis revealed that 1 is the first example of hybrid
peptide-polyketide possessing an unprecedented 5-hydroxy-2,2,4,6-tetramethyl-3-oxooctanoic acid moiety. The singlecrystal X-ray diffraction analyses allowed the absolute configuration assignment of this compound. Compound
1also exhibited significant insecticidal activities against Rhopalosiphum padi and Brevicoryne brassicae with LC50 values of 0.092 and 0.251 mM, respectively.

链接: http://pubs.acs.org/doi/abs/10.1021/acs.orglett.6b03568

全文:SQY-OL.pdf

 

Copyright (C) 兰州大学草地农业科技学院2009-2010 All Rights Reserved
地址:甘肃省兰州市嘉峪关西路768号 邮编:730020